2024 Grant Recipients:

• Debridement, Antibiotics, and Implant Retention (DAIR) versus Debridement, Antibiotics, and Fixation Revision (DAFR) for the Treatment of Fracture Related Infections PI: Natoli
• The Effect of Lower Extremity Non-union on Gait Speed: A Pilot Study PI: Natoli
• Return to Walk: Measuring Mobility Outcomes after Lower Extremity Amputation with Smartphone Data PI: Gage
• Assessment of Force Used During Lateral Stress Radiograph to Identify Occult Instability of Lateral Compression Pelvic Ring Injuries with Pressure Mapping Sensor PI: Lee
• Transverse Patellar Fracture Fixation with Wagon Wheel Construct Versus Anterior Tension Banding: A Biomechanical Cadaveric Study PI: Hidden
• Pre-clinical evaluation of a novel low-cost negative pressure wound therapy device designed for the resource-limited setting PI: Agarwal-Harding
• A Randomized Controlled Trial of Early versus Delayed Rehabilitation after Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture PI: Yarboro

2023 Grant Recipients:

• A Pilot Randomized Controlled trial comparing flap coverage within 72 hours versus standard of care in type IIIB lower extremity open fractures. PI: Mundy CO-PIs: Gage, Sprague
• PANTHER: Pain and Nicotine in Tibial Fracture healing & Early Recovery. PI:Little CO-PI: Marecek
• Is 2.7mm LCDCP Noninferior to 3.5mm in diaphyseal forearm fractures. PI: Vialonga, CO-PI: Yoon
• Using Next Generation Sequencing to Define the Microbiome of gunshot related long bone fractures. PI: Dehghani CO-PI: Mehta
• Reevaluating tibial plateau fractures using standard alignment parameters. PI:Marecek CO-PI:Scolaro
• Safety of Brain and Cervical MRI in Unresponsive Patients with External fixators. PI: Kazley CO-PI: Swart
• The Role of Fracture Hematoma and Soft Callus in Bone Healing. PI: Ricci
• Assessment of Unique Radiographic Markers for Reduction of Ankle Syndesmosis. PI: Mir CO-PI: Stockwell

2022 Grant Recipients:

• Biomechnanical Evaluation of Suture Augmentation of locking plate Fixation in Patella Fractures
  PI: Scolaro, Co-PI: Chalmers
• A Novel antibiotic to reduce fracture related infection in a murine model. PI: Sorkin, Co-PI’s: Greenfield, Suryanashi
• Prospective Analysis of Progenitor Cell Phenotype: A pilot study in Patients with long bone fractures PI: Ahn, Co-PI: Alford
• Characterization of the Pathologic Variance in Pediatric Acute and Chronic Osteomyelitis via a Clinically-Translatable Bacterial and Biofilm Visualization Assay PI: Born, Co-PI: Garcia

2021 Grant Recipients:

• Biomechanical Evaluation of Plate – Nail Fixation Constructs in Proximal Tibia Fractures. PI-Scolaro, Co-PI Lai
• Systemic Immune Dysregulation in Patients with Severe Tibia Fractures. PI-Hernandez-Irizarry
• Nerve-Artery Interposition for Neuroma Prevention. PI-Watson, Co-PI’s Dhawan;Gagyi, Ragsdale
• The use of external beam radiation therapy for heterotopic ossification prophylaxis after surgical fixation of acetabular fractures: a multi-center randomized controlled trial. PI-Pollak, CO-PI’s,Boissonneault;O’Toole
• The Role of Blood Flow Restriction Therapy in the Postop Rehabilitation of Older Adult Patients (age >65) with Hip Fractures: A Randomized Controlled Pilot Study. PI-Spitler

2020 Grant Recipients:

• Silver Carboxylate Eluting Titanium Dioxide-Polidmethyl Siloxane Antimicrobial as an Effective Wound Care antimicrobial against Biofilm- Forming Antiobiotic-resistant Baceteria and Persister Cells. PI Born, Co- PI Garcia
• Local Multimodal Injection vs. Single Shot Regional Anesthesia for Pain control in Rotational Ankle fractures: A Prospective, Randomized, Controlled trial. PI: Haller, Co-PI Marchand
• Weight Bearing After Geriatric Femur Fractures: A Prospective, Objective Analysis of Population Norms and Predictors of Delayed Progression. PI: Gardner
• Outcomes of Femoral Neck Nonunion Surgery: A Radiographic and Gait Analysis. PI: Beltran, Co-PI: Collinge
• Does the Use of Broad-Spectrum Antibiotic Powder on Initial Presentation of Grade III Open lower extremity fractures in the emergency Department Prior to Surgery reduce infection rates and need for return to Operating Room for Revision Surgery within Six months of Injury? PI-Mir
• Does Intraoperative Fluid Pooling at the end of drapes during lower extremity surgery lead to the introduction of Novel Bacteria to the Surgical Field? PI: Seligson Co-PI-Likine
• Optimizing the Disinfection of Devitilized Bone for Retained Use in Open Fractures: An In Vitro Study. PI: Ricci Co-PI’s Dvoszhinksy, Wellman

2019 Grant Recipients:

• Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Alleviation in Perioperative Fx. Patients. PI-Kempton
• Operartive vs. Non-Operative Fixation of Posterior Malleolar Fx. Involving less than 25% of the Articular Surface: A Single institution randomized controlled trial. PI: YUAN
• Self-Directed Home Exercise therapy vs. Formal Occupational Therapy Following Selected Upper Extremity Fractures: A Randomized Controlled Pilot Feasibility Trial. PI: Pollak
• A biomechanical comparison of interfragmentary positional vs. lag screw fixation in an osteoporotic bone model. PI: Donahue
• Telerehabilitation Following surgical fixation of ankle fractures: A Pilot Study. PI: McLaughlin Co-PI: Osgood
• A Pilot Prospective Randomized Trial Evaluating Regional Anesthesia, Long-Acting Local Anesthesia and Traditional Care for Pain Control of Operatively Treated Ankle Fractures. PI: Swart
• Use of Immunologic Rapid Assay as a Detection of Bacterial Contamination and Endotoxin Presence on Implants and Allograft Tissue PI: Born, Co-PI’s Garcia and Owens
• Biomechanical Comparison of Interfragmentary Compression in Sacral Fractures. PI: Marecek

2018 Grant Recipients:

• A Rat Model for Preserving Chondrocyte Viability after Closed Intra-articular fracture. PI: Greisberg
• Development of a Patient Reported Outcome Instrument for Severe Lower Extremity Trauma: Cognitive Debriefing Interiews. PI: Gage
• Mitigating the Effect of Hemodynamic Shock on Fracture and Muscle Healing Using Non-Selective Systemic Immunomodulation. PI: Sorkin/Natoli
• Biodegradable 3D-Printed Scaffold to Treat post-traumatic osteoarthritis. PI: DeLong
• Novel Biomechanical Model Assessing Four-Part Proximal Humerus Fractures. PI: Scolaro
• Use of Low Dose Post Op Protocol after Acetabular Surgery. PI: Mir
• Reducing Opiod Utilization in the Emergency Management of Common Orthopaedics Manipulations. PI: Schenker

2017 Grant Recipients:

• Masquelet Technique: Effect of Spacer porosity on membrane formation and bone regeneration. PI: Watson
• Effect of local anesthetic on fracture healing in an animal model. PI: Donegan
• Assessment of Force used during stress examination of posterior wall acetabular fractures using hand-held dynamometry. PI: Lee, Collinge
• E-cigarette use and fracture healing: An Animal exposure study. PI: Prasarn
• Comparison of topic tranexamic acid to routine hemostasis in surgical fixation of traumatic spinal injuries: a double blinded placebo controlled randomized trial. Co-PI: Pollak
• Opioid prescribing patterns and relation to patient satisfaction scores for orthopedic trauma patients. PI: Mir
• Outcomes of Multiligament knee injuries. PI: Sciadini

2016 Grant Recipients:

• Intramedullary Kirschner Wire Versus Flexible Nail Fixation for Pediatric Femur Fractures. PI: Morshed
• The Impact of Topical Tranexamic Acid on Pre- and Post-Operative Hemoglobin/Hematocrit in Isolated Operative Posterior Wall Acetabular Fractures: A Prospective, Randomized, Double-Blind, Multi-Center Study. PI: Archdeacon
• Early weight bearing for unstable ankle fractures undergoing operative stabilization: is it safe and does it improve outcomes? PI: Tejwani
• Validation of a New Surgical Simulator for Fluoroscopically Guided Procedures IRB Approval- University of Maryland, Baltimore. PI: Sciadini
• The mechanical effect of blocking screws in geriatric supracondylar femur fractures treated with intramedullary fixation. PI: Mir
• Assessing Coagulopathy in Trauma Patients with Pelvic and Acetabular Fractures. PI: Sagi
• A pilot feasibility study of role of vitamin D in regulation of bone homeostasis in orthopaedic trauma patients. PI: Sen
• Rapid Detection and Quantification of Biofilms on Orthopaedic Implants. PI: Born

2015 Grant Recipients:

• Effects of fatigue on cognitive and psychomotor performance in orthopaedic house staff. PI:Mehta
• Early weight bearing on supracondylar distal femur fractures in elderly patients. PI: Cannada
• Prospective, randomized trial of removal vs. non-removal of percutaneously placed IS screws in pelvic ring fx. PI: Sciadini
• Femoral neck exposure via Watson Jones approach compared to modified Smith Peterson approach: A cadaveric study. PI: Bishop

2014 Grant Recipients:

• Acceleration of geriatric fracture healing by local activation of notch signaling. PI: Ahn
• Biomechanical Evaluation of Fixation Strategies for Vertically Oriented Femoral Neck Fractures in a Clinically Relevant Model. PI: Scolaro
• A Complete Analysis of the Cost of Ankle Fractures. PI: Vosseller
• Relating Fracture Severity and Outcomes in Tibial Plateau and Pilon Fractures. PI: Sorkin
• Innervation during fracture repair: exploring functional mechanisms and innovative therapeutic strategies. PI: Miclau
• The Role of Skin Microbiota in the Development of Infections following open fractures. PI: Hak

2013 Grant Recipients:

• Removal of Syndesmotic screws: is there an advantage? PI: Tornetta
• Syndesmosis Reduction: Clamp force and functional outcomes. PI: Gardner
• The Effects of Distal Radioulnar Joint Malunion on Patient outcomes after DRF. PI: Rosenwasser
• In Vivo Validation of Novel Engineered Bone Grafts for Large bone Defect repair. PI: Lowenberg

2012 Grant Recipients:

• Visualization and Quantification for Bacterial Biofilm on Orthopaedic Trauma Explants. PI: Born
• Immediate weight-bearing after distal tibia intramedullary fracture fixation-a biomechanical study of distal interlocking screw number and position. PI: Sagi
• Longitudinal morphologic and biomechanical characteristics of the knee after tibial cycle plateau fractures using MRI. PI: Morshed

2011 Grant Recipients:

• Endothelial Progenitor Cells for Acceleration of Bone Allograft Incorporation. PI: Watson et.al.
• Pedicle Screw Osteosynthesis for Vertically Unstable Sacral Fractures. PI: Mirza
• Ischemic Fracture Healing in the Absence of Thrombospondin 2. PI: Ahn
• Local Delivery of Leukotriene Inhibitors to Accelerate Fracture Healing in a Tibial Defect Model. PI: Hurwitz
• Comparison of Circumferential Blinder Devices in Unstable Pelvic Injuries: A Cadaveric Study. PI: Prasarn

2010 Grant Recipients:

• Factors Associated with Early Mortality Among Nursing Home Patients who Sustain Hip Fractures. PI: Pollak
• Enhancing Fracture Healing by the Homing if Mesenchymal Stem Cells Isolated from Medullary Reaming Materials. PI: Watson
• BMP Antagonist Interactions: Pilot Expression Profiling and Development of a Scalable Binding Assay. PI: Ahn
• Multicenter Proximal Tibia Registry-Expansion Year 1. PI: Koval
• Cost Effectiveness of Botulinum Toxin Injections for Prevention of Post Traumatic Elbow Stiffness. PI: Rosenwasser

2009 Grant Recipients:

• Priming Endothelial Progenitor Cells with BMP-2 to Improve Angiogenesis and Osteogenesis in Fracture Nonunion. PI: Watson
• A Critical Assessment of Syndesmotic Reduction in Weber C Ankle Fractures. PI: Hak
• Performance of Ulnar Locking Plates on Fresh Cadaver Elbow under Physiologic Loads in a Neuro-muscular Simulator. PI: Tornetta
• Internet Usage Amongst Orthopaedic Trauma Patients. PI: Mehta
• The Role of Dicer During Fracture Repair has is approved for funding in the amount of. PI: Miclau

2008 Grant Recipients:

• Stability of Zone 2 Sacral Fractures: Does Trans-sacral fixation improve stiffness and strength? PI: Tornetta
• Locking plate vs. hemiarthroplasty for treatment of three and four part proximal humerus fractures in elderly patients: A prospective, randomized, multicenter study. PI: Gardner
• Qualitative differences of bone graft obtained with a reamer irrigator/aspirator and the iliac crest bone graft. PI: Sagi
• Biomechanics of locking plates and consequences of contouring. PI: Ricci
• Osteogenic capacity of mesenchymal stem cells derived from umbilical cord blood for enhancement of fracture healing. PI: Watson
• Multicenter proximal tibia registry study. PI: Koval

2007 Grant Recipients:

• Distal Radius Assessment and fx. Team study. PI: Koval
• A Prospective Study of Clinical outcomes following glenoid neck fxs. as correlated with quantitative assessment of osseous injury. PI: Tornetta
• The Role of BMP Antagonists in Fx. Healing. PI:Watson
• Weight Bearing as tolerated after placement of an IM nail for unstable tibial shaft fractures. PI: Osgood
• Functional outcomes of femoral neck fractures treated with cannulated screws. PI: Dickson
• Near Infrared Spectroscopy in Acute Compartment Syndrome. PI: Born
• Prospective Radiographic evaluation of patients with bicondylar proximal tibial fractures treated with single lateral locked plating. PI: Perez
• Randomized Control study of short vs. long dynamically locked gamma 3 nails for intertrochanteric hip fractures. PI: Probe
• Chondrocyte Apoptosis Following Blunt Trauma. PI: Greisberg
• Early Prediction Post-traumatic In-hospital Mortality in Pediatric Patients. PI: Koval
• Mesenchymal Stem Cell Counts in Bone Marrow from Non-Transmittal Sites. PI: Lyon
• Incidence of Genetic Polymorphisms and their influence on bone healing and nonunion in the hospital and general populations. PI: Miclau
• A Multicenter Prospective Cohort Study of Sacral Fractures Using Patient Based and Objective Outcomes. PI: Tornetta
• Proximal locking screws for nailing femoral shaft fracture: should cephalomedullary screw be the standard? PI: Collinge

2006 Grant Recipients:

• Complications associated with surgical treatment of pelvic ring injuries in the obese. PI-Sems
• Childbirth after Pelvic Fractures. PI: Cannada
• The effects of mediators on vascular permeability in ischemia-reperfusion injury. PI: Probe
• Locked volar plate versus external fixation for displaced intra-articular distal radius fractures: A prospective randomized trial. PI: Koval
• The Role of Muscle function in fracture healing. PI: Nork
• MRA Evaluation of Vascular injury in knee dislocations. PI: Born
• Biomechanical optimization of locked volar plating in complex intra-articular fractures of the distal radius. PI: Rosenwasser
• A Randomized Trial of antiglide vs. lateral plating for SE pattern Weber B pattern ankle fractures. PI: Tornetta
• Serum Hyaluronic Acid and dGEMRIC MRI Scanning to Predict Rapid Progression of Cartilage Degeneration after Articular Fracture. PI: Dirschl